7 Aug 2026, 22:49 UTC28 viewsread 7 August 2026 Intrauterine exposure to captopril (and all other ACE inhibitors and angiotensin-receptor blockers) may increase risk of fetal malformations. During the 1 trimester, ACE inhibitor use may increase risk of central nervous system and cardiac malformations. Use during later pregnancy may increase risk of oligohydramnios, which puts the fetus at risk of fetal pulmonary hypoplasia and death.
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7 Aug 2026, 22:46 UTC30 viewsread 7 August 2026 Antenatal exposure to SSRIs in late pregnancy may result in neonatal behavioral syndrome (poor neonatal adaptation), characterized by hypothermia, vomiting, frequent stools, feeding difficulties, poor sleep, excessive crying, agitation, irritability, tremors, jitteriness, respiratory problems, hypoglycemia, seizures, and/or hypertonia/hyperreflexia or hypotonia.
Most infants with neonatal behavioral syndrome require …
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6 Aug 2026, 18:04 UTC190 views2 reactionsread 7 August 2026 Photo
Isolated polydactyly is often autosomal dominant, while syndromic polydactyly is often autosomal recessive. Postaxial polydactyly is approximately 10x more frequent in African Amricans than in Caucasians and is more frequent in male children. Ulnar polydactyly is seen in association with Meckel syndrome, Ellis-van-Creveld syndrome, Down syndrome, and Smith-Lemli-Opitz syndrome.
Radial polydactyly is seen in associati…
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6 Aug 2026, 17:54 UTC192 viewsread 7 August 2026 Cutis marmorata telangiectatica congenita, characterized by localized or generalized reddish-violaceous or bluish-purple mottling in a reticulated pattern. It is often reported in association with a variety of other congenital anomalies, including but not limited to undergrowth or overgrowth of an involved extremity.
In contrast to physiologic cutis marmorata (the normal vascular response to cold in the newborn), i…
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6 Aug 2026, 17:54 UTC171 viewsread 7 August 2026 Photo
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6 Aug 2026, 17:29 UTC181 views1 reactionsread 7 August 2026 Photo
#exam_trick
Hirschsprung disease vs meconium ileus vs meconium plug
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5 Aug 2026, 18:47 UTC239 views3 reactionsread 7 August 2026 Urine organic acids
Newborn screening
Plasma amino acids
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5 Aug 2026, 18:45 UTC239 viewsread 7 August 2026 Photo
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4 Aug 2026, 18:43 UTC280 views2 reactionsread 7 August 2026 File
Paediatric Critical Care Manual 2nd Edition 2024
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3 Aug 2026, 15:47 UTC368 views2 reactionsread 7 August 2026 Photo
#exam_trick
2nd trimester quadruple screening
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3 Aug 2026, 15:39 UTC354 viewsread 7 August 2026 In addition to NTDs, elevated AFP also can be seen in multiple gestation and abdominal wall defects (omphalocele and gastroschisis).
(Low levels of α-fetoprotein may be associated with both trisomy 18 and 21.)
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3 Aug 2026, 15:20 UTC354 viewsread 7 August 2026 Photo
Caudal regression syndrome is ~ 200× more frequent among infants of diabetic mothers (IDMs) when compared to other infants.
A wide range of structural defects occur in caudal regression syndrome, including incomplete to absent development of the sacrum and, to a lesser extent, the lumbar vertebrae. Associated spinal cord dysfunction results in varying degrees of neurologic impairment of bowel and lower extremity fun…
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